Dual targeting of l-carnitine-conjugated nanoparticles to OCTN2 and ATB0,+ to deliver chemotherapeutic agents for colon cancer therapy
l-Carnitine, obligatory for oxidation of fatty acids, is transported into cells by the Na+-coupled transporter OCTN2 and the Na+/Cl--coupled transporter ATB0,+. Here we investigated the potential of L-carnitine-conjugated poly(lactic-co-glycolic acid) (PLGA) nanoparticles (LC-PLGA NPs) to deliver ch...
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| Main Authors: | , , , , , , , , |
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| Format: | Book |
| Published: |
Taylor & Francis Group,
2017-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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