Recent Advances in Translational Pharmacokinetics and Pharmacodynamics Prediction of Therapeutic Antibodies Using Modeling and Simulation

• Main Authors: Kenta Haraya (Author), Haruka Tsutsui (Author), Yasunori Komori (Author), Tatsuhiko Tachibana (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2022-04-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Therapeutic monoclonal antibodies (mAbs) have been a promising therapeutic approach for several diseases and a wide variety of mAbs are being evaluated in clinical trials. To accelerate clinical development and improve the probability of success, pharmacokinetics and pharmacodynamics (PKPD) in human...