A Chymase Inhibitory RNA Aptamer Improves Cardiac Function and Survival after Myocardial Infarction

• Asıl Yazarlar: Denan Jin (Yazar), Shinji Takai (Yazar), Yosuke Nonaka (Yazar), Satoko Yamazaki (Yazar), Masatoshi Fujiwara (Yazar), Yoshikazu Nakamura (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2019-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

We have reported that mast cell chymase, an angiotensin II-generating enzyme, is important in cardiovascular tissues. Recently, we developed a new chymase-specific inhibitory RNA aptamer, HA28, and we evaluated the effects of HA28 on cardiac function and the mortality rate after myocardial infarctio...