No association of CDK5 genetic variants with Alzheimer's disease risk

• Main Authors: Combarros Onofre (Author), Berciano José (Author), Infante Jon (Author), Rodríguez-Rodríguez Eloy (Author), Sánchez-Juan Pascual (Author), Mateo Ignacio (Author), Vázquez-Higuera José (Author)
• Format: Book
• Published: BMC, 2009-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>As cyclin-dependent kinase 5 (CDK5) has been implicated in the abnormal hyperphosphorylation of tau in Alzheimer's disease (AD) brain, and the development of neurofibrillary tangles, we examined the contribution of this gene to...