Inhibitory effects of berberine on proinflammatory M1 macrophage polarization through interfering with the interaction between TLR4 and MyD88

• Main Authors: Jing Gong (Author), Jingbin Li (Author), Hui Dong (Author), Guang Chen (Author), Xin Qin (Author), Meilin Hu (Author), Fen Yuan (Author), Ke Fang (Author), Dingkun Wang (Author), Shujun Jiang (Author), Yan Zhao (Author), Wenya Huang (Author), Zhaoyi Huang (Author), Fuer Lu (Author)
• Format: Book
• Published: BMC, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Backgrounds Inflammation is recognized as the key pathological mechanism of type 2 diabetes. The hypoglyceamic effects of berberine (BBR) are related to the inhibition of the inflammatory response, but the mechanism is not completely clear. Methods The inflammatory polarization of Raw264.7...