The Ionotropic P2X4 Receptor has Unique Properties in the Heart by Mediating the Negative Chronotropic Effect of ATP While Increasing the Ventricular Inotropy
Background: Mounting evidence indicate that reducing the sinoatrial node (SAN) activity may be a useful therapeutic strategy to control of heart failure. Purines, like ATP and its metabolite adenosine, consistently reduce the SAN spontaneous activity leading to negative cardiac chronotropy, with var...
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| Main Authors: | , , , , |
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| Format: | Book |
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Frontiers Media S.A.,
2019-09-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |