Caspase-11 Mediates Pyroptosis of Tubular Epithelial Cells and Septic Acute Kidney Injury

• Main Authors: Zhiming Ye (Author), Li Zhang (Author), Ruizhao Li (Author), Wei Dong (Author), Shuangxin Liu (Author), Zhilian Li (Author), Huaban Liang (Author), Lifen Wang (Author), Wei Shi (Author), Asrar B. Malik (Author), Kwong Tai Cheng (Author), Xinling Liang (Author)
• Format: Book
• Published: Karger Publishers, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Acute kidney injury (AKI) is a serious complication of sepsis and has a high morbidity and mortality rate. Caspase-11 induces pyroptosis, a form of programmed cell death that plays a critical role in endotoxic shock, but its role in tubular epithelial cell death and whether it contr...