Evaluation and Optimization of Prolonged Release Mucoadhesive Tablets of Dexamethasone for Wound Healing: In Vitro-In Vivo Profiling in Healthy Volunteers

• Main Authors: Qurrat ul Ain Javed (Author), Muhammad Ali Syed (Author), Rabia Arshad (Author), Abbas Rahdar (Author), Muhammad Irfan (Author), Syed Atif Raza (Author), Gul Shahnaz (Author), Sana Hanif (Author), Ana M. Díez-Pascual (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of the projected study was to design and develop a novel strategy for evaluating the mucoadhesive potential of polymeric tablets of dexamethasone (DXM) for local delivery against wounds. Therefore, formulations (Q1-Q7) were synthesized via direct compression method by varying the concentrati...