Peripheral Neuropathy During Concomitant Administration of Proteasome Inhibitors and Factor Xa Inhibitors: Identifying the Likelihood of Drug-Drug Interactions

• Үндсэн зохиолчид: Long Meng (Зохиогч), Jing Huang (Зохиогч), Feng Qiu (Зохиогч), Xuefeng Shan (Зохиогч), Lin Chen (Зохиогч), Shusen Sun (Зохиогч), Yuwei Wang (Зохиогч), Junqing Yang (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Backgrounds: Proteasome inhibitors (PI) cause toxic peripheral neuropathy (PN), which is one of the dose-limiting adverse events of these treatments. Recent preclinical studies find that factor Xa inhibitor (FXaI), rivaroxaban, promotes PN in animals receiving oxaliplatin. Cancer patients can receiv...