LC-MS/MS assay for pitavastatin in human plasma and subsequent application to a clinical study in healthy Chinese volunteers

• Main Authors: Tengrui Yin (Author), Qian Liu (Author), Hui Zhao (Author), Lirong Zhao (Author), Hui Liu (Author), Miao Li (Author), Meilan Cui (Author), Wengang Ren (Author)
• Format: Book
• Published: Elsevier, 2014-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A rapid, selective and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed and validated for the determination of pitavastatin in human plasma. Following a liquid-liquid extraction, both the analytes and internal standard telmisartan were separated on a Luna...