Venlafaxine-Induced Cytotoxicity Towards Isolated Rat Hepatocytes Involves Oxidative Stress and Mitochondrial/Lysosomal Dysfunction

• Main Authors: Elham Ahmadian (Author), Hossein Babaei (Author), Alireza Mohajjel Nayebi (Author), Aziz Eftekhari (Author), Mohammad Ali Eghbal (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2016-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Depression is a public disorder worldwide. Despite the widespread use of venlafaxine in the treatment of depression, it has been associated with the incidence of toxicities. Hence, the goal of the current investigation was to evaluate the mechanisms of venlafaxine-induced cell death in the...