Impact of short-term discontinuation of ivermectin-based chemoprevention on onchocerciasis transmission in endemic settings with long history of mass drug administration.

• Main Authors: Arnauld Efon-Ekangouo (Author), Hugues C Nana-Djeunga (Author), Narcisse Nzune-Toche (Author), Raïssa Dongmo-Yemele (Author), Jean Bopda (Author), Viviane Ongbassomben (Author), Laurentine Sumo (Author), Anne Geiger (Author), Thomas B Nutman (Author), Joseph Kamgno (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>The control of onchocerciasis currently relies on annual distribution of single dose ivermectin. Because ivermectin has minimal effects on the adult parasite, mass drug administration (MDA) campaigns against onchocerciasis require at least 15 years of annual uninterrup...