Nanoparticles Based on Cross-Linked Poly(Lipoic Acid) Protect Macrophages and Cardiomyocytes from Oxidative Stress and Ischemia Reperfusion Injury

• Main Authors: Chiara Bellini (Author), Salvatore Antonucci (Author), Lucía Morillas-Becerril (Author), Sara Scarpa (Author), Regina Tavano (Author), Fabrizio Mancin (Author), Fabio Di Lisa (Author), Emanuele Papini (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The control of radical damage and oxidative stress, phenomena involved in a large number of human pathologies, is a major pharmaceutical and medical goal. We here show that two biocompatible formulations of Pluronic-stabilized, poly (lipoic acid)-based nanoparticles (NP) effectively antagonized the...