Inhibitory Effect of Trimidox on Lipopolysaccharide-Induced Nitric Oxide Production in RAW 264.7 Macrophages

Inhibitory Effect of Trimidox on Lipopolysaccharide-Induced Nitric Oxide Production in RAW 264.7 Macrophages

We examined the effect of trimidox (3,4,5-trihydroxybenzamidoxime) on the production of nitric oxide (NO) by lipopolysaccharide (LPS) in mouse RAW 264.7 macrophages. Trimidox (50 - 300 µM) concentration-dependently inhibited NO production by LPS (0.01, 0.1, or 1 µg/ml) after incubation for 24 h. LPS...

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Main Authors: Syu-ichi Kanno (Author), Mai Kakuta (Author), Yasue Kitajima (Author), Yuu Osanai (Author), Kaori Kurauchi (Author), Takaharu Ohtake (Author), Mayuko Ujibe (Author), Kouji Uwai (Author), Mituhiro Takeshita (Author), Masaaki Ishikawa (Author)
Format: Book
Published: Elsevier, 2007-01-01T00:00:00Z.
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