Mono and Multiple Tumor-Targeting Ligand-Coated Ultrasmall Gadolinium Oxide Nanoparticles: Enhanced Tumor Imaging and Blood Circulation

• Main Authors: Son Long Ho (Author), Huan Yue (Author), Sangyeol Lee (Author), Tirusew Tegafaw (Author), Mohammad Yaseen Ahmad (Author), Shuwen Liu (Author), Abdullah Khamis Ali Al Saidi (Author), Dejun Zhao (Author), Ying Liu (Author), Sung-Wook Nam (Author), Kwon Seok Chae (Author), Yongmin Chang (Author), Gang Ho Lee (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hydrophilic and biocompatible PAA-coated ultrasmall Gd₂O₃ nanoparticles (d_avg = 1.7 nm) were synthesized and conjugated with tumor-targeting ligands, i.e., cyclic arginylglycylaspartic acid (cRGD) and/or folic acid (FA). FA-PAA-Gd&...