α-Glucosidase inhibition by flavonoids: an in vitro and in silico structure-activity relationship study

• Main Authors: Carina Proença (Author), Marisa Freitas (Author), Daniela Ribeiro (Author), Eduardo F. T. Oliveira (Author), Joana L. C. Sousa (Author), Sara M. Tomé (Author), Maria J. Ramos (Author), Artur M. S. Silva (Author), Pedro A. Fernandes (Author), Eduarda Fernandes (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

α-Glucosidase inhibitors are described as the most effective in reducing post-prandial hyperglycaemia (PPHG) from all available anti-diabetic drugs used in the management of type 2 diabetes mellitus. As flavonoids are promising modulators of this enzyme's activity, a panel of 44 flavonoids, org...