Master and servant: LINC00152 - a STAT3-induced long noncoding RNA regulates STAT3 in a positive feedback in human multiple myeloma

• Main Authors: Stefanie Binder (Author), Ivonne Zipfel (Author), Maik Friedrich (Author), Diana Riedel (Author), Stefanie Ende (Author), Christoph Kämpf (Author), Karolin Wiedemann (Author), Tilo Buschmann (Author), Sven-Holger Puppel (Author), Kristin Reiche (Author), Peter F. Stadler (Author), Friedemann Horn (Author)
• Format: Book
• Published: BMC, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The survival of INA-6 human multiple myeloma cells is strictly dependent upon the Interleukin-6-activated transcription factor STAT3. Although transcriptional analyses have revealed many genes regulated by STAT3, to date no protein-coding STAT3 target gene is known to mediate sur...