Pharmacokinetic Boosting of Kinase Inhibitors
(1) Introduction: Pharmacokinetic boosting of kinase inhibitors can be a strategy to enhance drug exposure and to reduce dose and associated treatment costs. Most kinase inhibitors are predominantly metabolized by CYP3A4, enabling boosting using CYP3A4 inhibition. Kinase inhibitors with food enhance...
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MDPI AG,
2023-04-01T00:00:00Z.
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