Multikinase Abl/DDR/Src Inhibition Produces Optimal Effects for Tyrosine Kinase Inhibition in Neurodegeneration

• Egile Nagusiak: Alan J. Fowler (Egilea), Michaeline Hebron (Egilea), Alexander A. Missner (Egilea), Ruchong Wang (Egilea), Xiaokong Gao (Egilea), Bahjat T. Kurd-Misto (Egilea), Xiaoguang Liu (Egilea), Charbel E.-H. Moussa (Egilea)
• Formatua: Liburua
• Argitaratua: Adis, Springer Healthcare, 2019-03-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Background and objectives Inhibition of Abelson (Abl) tyrosine kinase as a therapeutic target has been gaining attention in neurodegeneration. Post-mortem Alzheimer's and Parkinson's disease brains show that the levels of several other tyrosine kinases, including Discoidin Domain...