Fixed vs adjusted-dose benznidazole for adults with chronic Chagas disease without cardiomyopathy: A systematic review and meta-analysis.

• Main Authors: Agustín Ciapponi (Author), Fabiana Barreira (Author), Lucas Perelli (Author), Ariel Bardach (Author), Joaquim Gascón (Author), Israel Molina (Author), Carlos Morillo (Author), Nilda Prado (Author), Adelina Riarte (Author), Faustino Torrico (Author), Isabela Ribeiro (Author), Juan Carlos Villar (Author), Sergio Sosa-Estani (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chagas disease is a neglected disease that remains a public health threat, particularly in Latin America. The most important treatment options are nitroimidazole derivatives, such as nifurtimox and benznidazole (BZN). Some studies suggest that for adults seropositive to T. cruzi but without clinical...