Co-delivery of metformin and levofloxacin hydrochloride using biodegradable thermosensitive hydrogel for the treatment of corneal neovascularization

• Main Authors: Dong Liu (Author), Qianni Wu (Author), Yuqiong Zhu (Author), Yijun Liu (Author), Xiuli Xie (Author), Sihan Li (Author), Haotian Lin (Author), Weirong Chen (Author), Fangming Zhu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Corneal neovascularization (CNV) is one of the major causes of severe disorders in ocular surface. Subconjunctival administration provides a localized and effective delivery of anti-angiogenic agents to inhibit neovascularization. In the present study, the ABA triblock copolymer of poly(D,L-lactic-c...