Identification of a novel heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) ligand that disrupts HnRNPA2B1/nucleic acid interactions to inhibit the MDMX-p53 axis in gastric cancer

• Main Authors: Lei Hu (Author), Shuqi Liu (Author), Hongying Yao (Author), Yuemiao Hu (Author), Yingjie Wang (Author), Jingpeng Jiang (Author), Xiaopeng Li (Author), Fenghua Fu (Author), Qikun Yin (Author), Hongbo Wang (Author)
• Format: Book
• Published: Elsevier, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gastric carcinoma is a highly malignant tumor that still lacks effective molecular targets. Heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) is an essential oncogenic driver overexpressed in various cancers. The potential role of hnRNPA2B1 in oncotherapy has not been revealed because of the...