Anti-tumor Activity of miniPEG-γ-Modified PNAs to Inhibit MicroRNA-210 for Cancer Therapy

Anti-tumor Activity of miniPEG-γ-Modified PNAs to Inhibit MicroRNA-210 for Cancer Therapy

MicroRNAs (miRs) are frequently overexpressed in human cancers. In particular, miR-210 is induced in hypoxic cells and acts to orchestrate the adaptation of tumor cells to hypoxia. Silencing oncogenic miRs such as miR-210 may therefore offer a promising approach to anticancer therapy. We have develo...

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Main Authors: Anisha Gupta (Author), Elias Quijano (Author), Yanfeng Liu (Author), Raman Bahal (Author), Susan E. Scanlon (Author), Eric Song (Author), Wei-Che Hsieh (Author), Demetrios E. Braddock (Author), Danith H. Ly (Author), W. Mark Saltzman (Author), Peter M. Glazer (Author)
Format: Book
Published: Elsevier, 2017-12-01T00:00:00Z.
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