Synthesis, antimycobacterial evaluation, and molecular docking study of 1,2,4-triazole derivatives

Fifteen 1,2,4-triazole derivatives were synthesised in this study and their MIC values against Mycobacterium tuberculosis (Mtb) ranged from 2 to 32 μg/mL. Furthermore, their antimycobacterial activity was positively correlated with the KatG enzyme docking score. Among the 15 compounds, compound 4 sh...

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Main Authors: Meng-Yu Xia (Author), Yu-Xiang Cai (Author), Jun-Xian Chen (Author), Xin Zhao (Author), Hong-Mei Dong (Author), Zai-Chang Yang (Author)
Format: Book
Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
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