Evaluating Known Zika Virus NS2B-NS3 Protease Inhibitor Scaffolds via In Silico Screening and Biochemical Assays

Evaluating Known Zika Virus NS2B-NS3 Protease Inhibitor Scaffolds via In Silico Screening and Biochemical Assays

The NS2B-NS3 protease (NS2B-NS3pro) is regarded as an interesting molecular target for drug design, discovery, and development because of its essential role in the Zika virus (ZIKV) cycle. Although no NS2B-NS3pro inhibitors have reached clinical trials, the employment of drug-like scaffolds can faci...

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Main Authors: Lucianna H. Santos (Author), Rafael E. O. Rocha (Author), Diego L. Dias (Author), Beatriz M. R. M. Ribeiro (Author), Mateus Sá M. Serafim (Author), Jônatas S. Abrahão (Author), Rafaela S. Ferreira (Author)
Format: Book
Published: MDPI AG, 2023-09-01T00:00:00Z.
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3rd Floor Main Library

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