Evaluating Known Zika Virus NS2B-NS3 Protease Inhibitor Scaffolds via In Silico Screening and Biochemical Assays
The NS2B-NS3 protease (NS2B-NS3pro) is regarded as an interesting molecular target for drug design, discovery, and development because of its essential role in the Zika virus (ZIKV) cycle. Although no NS2B-NS3pro inhibitors have reached clinical trials, the employment of drug-like scaffolds can faci...
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Main Authors: | Lucianna H. Santos (Author), Rafael E. O. Rocha (Author), Diego L. Dias (Author), Beatriz M. R. M. Ribeiro (Author), Mateus Sá M. Serafim (Author), Jônatas S. Abrahão (Author), Rafaela S. Ferreira (Author) |
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Format: | Book |
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MDPI AG,
2023-09-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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