ELAC2/RNaseZ-linked cardiac hypertrophy in Drosophila melanogaster

• Autores principales: Ekaterina Migunova (Autor), Joanna Theophilopoulos (Autor), Marisa Mercadante (Autor), Jing Men (Autor), Chao Zhou (Autor), Edward B. Dubrovsky (Autor)
• Formato: Libro
• Publicado: The Company of Biologists, 2021-08-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

A severe form of infantile cardiomyopathy (CM) has been linked to mutations in ELAC2, a highly conserved human gene. It encodes Zinc phosphodiesterase ELAC protein 2 (ELAC2), which plays an essential role in the production of mature tRNAs. To establish a causal connection between ELAC2 variants and...