Tuning Design Parameters of ICAM-1-Targeted 3DNA Nanocarriers to Optimize Pulmonary Targeting Depending on Drug Type
3DNA holds promise as a carrier for drugs that can be intercalated into its core or linked to surface arms. Coupling 3DNA to an antibody targeting intercellular adhesion molecule 1 (ICAM-1) results in high lung-specific biodistributions in vivo. While the role of individual parameters on ICAM-1 targ...
Saved in:
Main Authors: | Nikša Roki (Author), Melani Solomon (Author), Jessica Bowers (Author), Lori Getts (Author), Robert C. Getts (Author), Silvia Muro (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2022-07-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
A method to improve quantitative radiotracing‐based analysis of the in vivo biodistribution of drug carriers
by: Nikša Roki, et al.
Published: (2021) -
B-Cell-Targeted 3DNA Nanotherapy Against Indoleamine 2,3-Dioxygenase 2 (IDO2) Ameliorates Autoimmune Arthritis in a Preclinical Model
by: Lauren MF Merlo, et al.
Published: (2020) -
A Strategy for Selective Deletion of Autoimmunity-Related T Cells by pMHC-Targeted Delivery
by: Shalom D. Goldberg, et al.
Published: (2021) -
Targeting sites of inflammation:Intercellular adhesion molecule-1 (ICAM-1) as a target for novel inflammatory therapies
by: Susan eHua
Published: (2013) -
B7-H3 and ICAM-1 are potentially therapeutic targets for thyroid carcinoma
by: Pengtao Song, et al.
Published: (2024)