Paeoniflorin alleviates 17α-ethinylestradiol-induced cholestasis via the farnesoid X receptor-mediated bile acid homeostasis signaling pathway in rats

• Κύριοι συγγραφείς: Rulin Wang (Συγγραφέας), Tengteng Yuan (Συγγραφέας), Jing Sun (Συγγραφέας), Menghuan Yang (Συγγραφέας), Yunna Chen (Συγγραφέας), Lei Wang (Συγγραφέας), Yanyan Wang (Συγγραφέας), Weidong Chen (Συγγραφέας), Daiyin Peng (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Cholestasis, characterized by disturbance of bile formation, is a common pathological condition that can induce several serious liver diseases. As a kind of trigger, estrogen-induced cholestasis belongs to drug-induced cholestasis. Paeoniflorin is the most abundant bioactive constituent in Paeonia l...