Reciprocal Relationship Between HDAC2 and P-Glycoprotein/MRP-1 and Their Role in Steroid Resistance in Childhood Nephrotic Syndrome

• Principais autores: Harshit Singh (Autor), Vikas Agarwal (Autor), Saurabh Chaturvedi (Autor), Durga Prasanna Misra (Autor), Akhilesh Kumar Jaiswal (Autor), Narayan Prasad (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background: Reduced HDACs levels have been reported in steroid resistant chronic obstructive pulmonary disease and bronchial asthma patients. P-glycoprotein (P-gp) over expression in peripheral blood mononuclear cells (PBMCs) has been reported in patients with steroid resistant nephrotic syndrome (N...