The impact of CYP2C19 genotype on phenoconversion by concomitant medication

• Main Authors: Laura M. de Jong (Author), Soukayna Boussallami (Author), Elena Sánchez-López (Author), Martin Giera (Author), Maarten E. Tushuizen (Author), Menno Hoekstra (Author), Lukas J. A. C. Hawinkels (Author), Robert Rissmann (Author), Jesse J. Swen (Author), Martijn L. Manson (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Pharmacogenetics-informed drug prescribing is increasingly applied in clinical practice. Typically, drug metabolizing phenotypes are determined based on genetic test results, whereupon dosage or drugs are adjusted. Drug-drug-interactions (DDIs) caused by concomitant medication can howe...