LTT and HLA testing as diagnostic tools in Spanish vancomycin-induced DRESS cases: A case-control study

• Main Authors: Teresa Bellón (Author), Victoria Lerma (Author), Javier Guijarro (Author), Elena Ramírez (Author), Celia Martínez (Author), Carmelo Escudero (Author), Ana M. Fiandor (Author), Ruth Barranco (Author), Manuel de Barrio (Author), Francisco de Abajo (Author), Rosario Cabañas (Author), PIELenRed Study Group (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe T-cell-mediated off-target adverse reaction. DRESS cases caused by vancomycin have often been reported. The HLA-A*32:01 allele has been associated with genetic susceptibility to vancomycin-induced DRESS in US citizens of Europ...