Model-based approach to the design of pharmaceutical roller-compaction processes

• المؤلفون الرئيسيون: Peter Toson (مؤلف), Diogo G. Lopes (مؤلف), Raphael Paus (مؤلف), Ashish Kumar (مؤلف), Jeroen Geens (مؤلف), Sandy Stibale (مؤلف), Julian Quodbach (مؤلف), Peter Kleinebudde (مؤلف), Wen-Kai Hsiao (مؤلف), Johannes Khinast (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2019-12-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

This work presents a new model based approach to process design and scale-up within the same equipment of a roller compaction process. The prediction of the operating space is not performed fully in-silico, but uses low-throughput experiments as input. This low-throughput data is utilized in an iter...