Urotensin II Induces Mice Skeletal Muscle Atrophy Associated with Enhanced Autophagy and Inhibited Irisin Precursor (Fibronectin Type III Domain Containing 5) Expression in Chronic Renal Failure

• Үндсэн зохиолчид: Ya-Jing Pan (Зохиогч), Si-Jia Zhou (Зохиогч), Jin Feng (Зохиогч), Qiong Bai (Зохиогч), La-Ta A (Зохиогч), Ai-Hua Zhang (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Karger Publishers, 2019-06-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Background/Aims: Skeletal muscle atrophy is one of the main manifestations of protein energy wasting. We hypothesized that urotensin II (UII) can lead to skeletal muscle atrophy through upregulating autophagy and affecting Irisin precursor fibronectin type III domain containing 5 (FNDC5) expressions...