AS1411 Aptamer Linked to DNA Nanostructures Diverts Its Traffic Inside Cancer Cells and Improves Its Therapeutic Efficacy
The nucleolin-binding G-quadruplex AS1411 aptamer has been widely used for cancer therapy and diagnosis and linked to nanoparticles for its selective targeting activity. We applied a computational and experimental integrated approach to study the effect of engineering AS1411 aptamer on an octahedral...
Saved in:
Main Authors: | Giulia Vindigni (Author), Sofia Raniolo (Author), Federico Iacovelli (Author), Valeria Unida (Author), Carmine Stolfi (Author), Alessandro Desideri (Author), Silvia Biocca (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2021-10-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Folate-Functionalization Enhances Cytotoxicity of Multivalent DNA Nanocages on Triple-Negative Breast Cancer Cells
by: Valeria Unida, et al.
Published: (2022) -
Nucleolin-Targeting AS1411 Aptamer-Conjugated Nanospheres for Targeted Treatment of Glioblastoma
by: Kyeongjin Seo, et al.
Published: (2024) -
Locking up the AS1411 Aptamer with a Flanking Duplex: Towards an Improved Nucleolin-Targeting
by: André Miranda, et al.
Published: (2021) -
The Bioactivity of D-/L-Isonucleoside- and 2'-Deoxyinosine-Incorporated Aptamer AS1411s Including DNA Replication/MicroRNA Expression
by: Xinmeng Fan, et al.
Published: (2017) -
AS1411-functionalized delivery nanosystems for targeted cancer therapy
by: Pooria Safarzadeh Kozani, et al.
Published: (2021)