Autophagy Upregulation and Apoptosis Downregulation in DAHP and Triptolide Treated Cerebral Ischemia

• Main Authors: Yang Yang (Author), Keqiang Gao (Author), Zhiying Hu (Author), Weiyun Li (Author), Henry Davies (Author), Shucai Ling (Author), John A. Rudd (Author), Marong Fang (Author)
• Format: Knjiga
• Izdano: Hindawi Limited, 2015-01-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

It has previously been demonstrated that ischemic stroke activates autophagy pathways; however, the mechanism remains unclear. The aim of this study is to further investigate the role that autophagy plays in cerebral ischemia. 2, 4-diamino-6-hydroxy-pyrimidine (DAHP), for its nitric oxide synthase (...