Tracking Radiolabeled Endothelial Microvesicles Predicts Their Therapeutic Efficacy: A Proof-of-Concept Study in Peripheral Ischemia Mouse Model Using SPECT/CT Imaging

• Egile Nagusiak: Romain Giraud (Egilea), Anaïs Moyon (Egilea), Stéphanie Simoncini (Egilea), Anne-Claire Duchez (Egilea), Vincent Nail (Egilea), Corinne Chareyre (Egilea), Ahlem Bouhlel (Egilea), Laure Balasse (Egilea), Samantha Fernandez (Egilea), Loris Vallier (Egilea), Guillaume Hache (Egilea), Florence Sabatier (Egilea), Françoise Dignat-George (Egilea), Romaric Lacroix (Egilea), Benjamin Guillet (Egilea), Philippe Garrigue (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Microvesicles, so-called endothelial large extracellular vesicles (LEVs), are of great interest as biological markers and cell-free biotherapies in cardiovascular and oncologic diseases. However, their therapeutic perspectives remain limited due to the lack of reliable data regarding their systemic...