An asparagine metabolism-based classification reveals the metabolic and immune heterogeneity of hepatocellular carcinoma

• Main Authors: Jianguo Bai (Author), Ruifeng Tang (Author), Keyu Zhou (Author), Jialei Chang (Author), Hongyue Wang (Author), Qixin Zhang (Author), Jiahui Shi (Author), Chao Sun (Author)
• Format: Book
• Published: BMC, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Introduction and objectives hepatocellular carcinoma (HCC) is the major form of liver cancer with a poor prognosis. Amino acid metabolism has been found to alter in cancers and contributes to malignant progression. However, the asparagine metabolism status and relevant mechanism in HCC were...