Preliminary study showing no association between G238A (rs361525) tumor necrosis factor-α (TNF-α) gene polymorphism and its serum level, hormonal and biochemical aspects of polycystic ovary syndrome

• Main Authors: Fahimeh Kordestani (Author), Sahar Mazloomi (Author), Yousef Mortazavi (Author), Saeideh Mazloomzadeh (Author), Mojtaba Fathi (Author), Haleh Rahmanpour (Author), Abolfazl Nazarian (Author)
• Format: Book
• Published: BMC, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Polycystic ovary syndrome (PCOS) is the main cause of female infertility. Interactions among genetic, biochemical, and immunological factors can affect the pathogenesis of PCOS. As a proinflammatory cytokine, tumor necrosis factor-α (TNF-α) plays an important role in this regard....