Targeted Delivery of Amantadine-loaded Methacrylate Nanosphere-ligands for the Potential Treatment of Amyotrophic Lateral Sclerosis

Targeted Delivery of Amantadine-loaded Methacrylate Nanosphere-ligands for the Potential Treatment of Amyotrophic Lateral Sclerosis

Purpose. This study aimed to develop and analyse poly(DL-lactic acid)-methacrylic acid nanospheres bound to the chelating ligand diethylenetriaminepentaacetic acid (DTPA)  for the targeted delivery of amantadine in Amyotrophic Lateral Sclerosis (ALS). Methods. The nanospheres were prepared by a doub...

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Main Authors: Zamanzima Mazibuko (Author), Sunaina Indermun (Author), Mershen Govender (Author), Pradeep Kumar (Author), Lisa C du Toit (Author), Yahya E Choonara (Author), Girish Modi (Author), Dinesh Naidoo (Author), Viness Pillay (Author)
Format: Book
Published: Frontiers Media S.A., 2018-03-01T00:00:00Z.
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3rd Floor Main Library

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