miR-126 contributes to the epigenetic signature of diabetic vascular smooth muscle and enhances antirestenosis effects of Kv1.3 blockers

• Main Authors: Marycarmen Arevalo-Martinez (Author), Pilar Cidad (Author), Sara Moreno-Estar (Author), Mirella Fernández (Author), Sebastian Albinsson (Author), Irene Cózar-Castellano (Author), José R. López-López (Author), M. Teresa Pérez-Garcia (Author)
• Format: Book
• Published: Elsevier, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Restenosis after vessel angioplasty due to dedifferentiation of the vascular smooth muscle cells (VSMCs) limits the success of surgical treatment of vascular occlusions. Type 2 diabetes (T2DM) has a major impact on restenosis, with patients exhibiting more aggressive forms of vascular di...