Genetic polymorphisms of the IL6 and NOD2 genes are risk factors for inflammatory reactions in leprosy.

• Main Authors: Carolinne Sales-Marques (Author), Cynthia Chester Cardoso (Author), Lucia Elena Alvarado-Arnez (Author), Ximena Illaramendi (Author), Anna Maria Sales (Author), Mariana de Andréa Hacker (Author), Mayara Garcia de Mattos Barbosa (Author), José Augusto da Costa Nery (Author), Roberta Olmo Pinheiro (Author), Euzenir Nunes Sarno (Author), Antonio Guilherme Pacheco (Author), Milton Ozório Moraes (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The pathways that trigger exacerbated immune reactions in leprosy could be determined by genetic variations. Here, in a prospective approach, both genetic and non-genetic variables influencing the amount of time before the development of reactional episodes were studied using Kaplan-Meier survival c...