Alpinetin suppresses CYP3A4, 2C9, and 2E1 activity in vitro

• Main Authors: Hongming Song (Author), Chuankui Wei (Author), Wu Yang (Author), Zhaohe Niu (Author), Mingkai Gong (Author), Haiyan Hu (Author), Haibo Wang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Alpinetin, the major active constitutes of Alpinia katsumata Hayata (Zingiberaceae), has been demonstrated to possess the activity of anti-breast cancer. Cytochrome P450 enzymes (CYP450s) plays vital roles in the biotransformation of various drugs.Objective To assess the effect of alpinetin...