Urolithin a attenuates IL-1β-induced inflammatory responses and cartilage degradation via inhibiting the MAPK/NF-κB signaling pathways in rat articular chondrocytes

• Main Authors: Sheng-long Ding (Author), Zhi-ying Pang (Author), Xue-mei Chen (Author), Zheng Li (Author), Xin-xin Liu (Author), Qi-lin Zhai (Author), Jun-ming Huang (Author), Zhi-yong Ruan (Author)
• Format: Book
• Published: BMC, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Osteoarthritis (OA) is characterized by inflammation and extracellular matrix (ECM) degradation and is one of the most common chronic degenerative joint diseases that causes pain and disability in adults. Urolithin A (UA) has been widely reported for its anti-inflammatory propert...