Fibroblast growth factor 21 enhances angiogenesis and wound healing of human brain microvascular endothelial cells by activating PPARγ

• Main Authors: Wenting Huang (Author), Mingjie Shao (Author), Huan Liu (Author), Jun Chen (Author), Jian Hu (Author), Liyun Zhu (Author), Fei Liu (Author), Dongxue Wang (Author), Yuchi Zou (Author), Ye Xiong (Author), Xue Wang (Author)
• Format: Book
• Published: Elsevier, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Angiogenesis of brain microvascular endothelial cells (BMECs) is required in the functional restoration of brain injury, such as traumatic brain injury (TBI) and ischemic stroke. Fibroblast growth factor 21 (FGF21) is an angiogenic molecule that functions through the formation of the FGF21/FGFR1/β-k...