Ena drives invasive macrophage migration in Drosophila embryos

• Main Authors: Philippa K. Tucker (Author), Iwan R. Evans (Author), Will Wood (Author)
• Format: Bog
• Udgivet: The Company of Biologists, 2011-01-01T00:00:00Z.
• Fag: article
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SUMMARY It is seldom the primary tumour that proves fatal in cancer, with metastasis the fundamental pathological process for disease progression. Upregulation of Mena, a member of the evolutionarily conserved Ena/VASP family of actin cytoskeletal regulators, promotes metastasis and invasive motilit...