Puerarin Attenuates Oxidative Stress and Ferroptosis via AMPK/PGC1α/Nrf2 Pathway after Subarachnoid Hemorrhage in Rats

• Main Authors: Yi Huang (Author), Honggang Wu (Author), Yongmei Hu (Author), Chenhui Zhou (Author), Jiawei Wu (Author), Yiwen Wu (Author), Haifeng Wang (Author), Cameron Lenahan (Author), Lei Huang (Author), Sheng Nie (Author), Xiang Gao (Author), Jie Sun (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Puerarin was shown to exert anti-oxidative and anti-ferroptosis effects in multiple diseases. The goal of this study was to explore the neuroprotective effect of puerarin on early brain injury (EBI) after subarachnoid hemorrhage (SAH) in rats. A total of 177 adult male Sprague Dawley rats were used....