CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder

CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder

Inhibition of p38 mitogen-activated protein kinase (MAPKs) is a potential therapeutic approach for the treatment of acute and chronic pulmonary inflammatory conditions. Here, we report the in vitro and in vivo characterization of the anti-inflammatory effects of CHF6297, a novel potent and selective...

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Main Authors: Cataldo Martucci (Author), Andrew Dennis Allen (Author), Nadia Moretto (Author), Valentina Bagnacani (Author), Alessandro Fioni (Author), Riccardo Patacchini (Author), Maurizio Civelli (Author), Gino Villetti (Author), Fabrizio Facchinetti (Author)
Format: Book
Published: Frontiers Media S.A., 2024-03-01T00:00:00Z.
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