Solubility and Stability Enhanced Oral Formulations for the Anti-Infective Corallopyronin A

• Main Authors: Anna K. Krome (Author), Tim Becker (Author), Stefan Kehraus (Author), Andrea Schiefer (Author), Christian Steinebach (Author), Tilman Aden (Author), Stefan J. Frohberger (Author), Álvaro López Mármol (Author), Dnyaneshwar Kapote (Author), Rolf Jansen (Author), Lillibeth Chaverra-Muñoz (Author), Marc P. Hübner (Author), Kenneth Pfarr (Author), Thomas Hesterkamp (Author), Marc Stadler (Author), Michael Gütschow (Author), Gabriele M. König (Author), Achim Hoerauf (Author), Karl G. Wagner (Author)
• Format: Book
• Published: MDPI AG, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Novel-antibiotics are urgently needed to combat an increase in morbidity and mortality due to resistant bacteria. The preclinical candidate corallopyronin A (CorA) is a potent antibiotic against Gram-positive and some Gram-negative pathogens for which a solid oral formulation was needed for further...