KLK10 exon 3 unmethylated PCR product concentration: a new potential early diagnostic marker in ovarian cancer? - A pilot study

• Main Authors: Mustafa A. El Sherbini (Author), Amal A. Mansour (Author), Maha M. Sallam (Author), Emtiaz A. Shaban (Author), Zeinab A. Shehab ElDin (Author), Amr H. El-Shalakany (Author)
• Formato: Livro
• Publicado em: BMC, 2018-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background KLK10 exon 3 hypermethylation correlated to tumor-specific lack of KLK10 expression in cancer cell lines and primary tumors. In the present study we investigate the possible role of KLK10 exon 3 methylation in ovarian tumor diagnosis and prognosis. Results Qualitative methylation...